There is scientific evidence for the old saying “Timing is everything!”. Researchers reported cyanobacteria takes up DNA in accordance with the circadian clock and can adapt to seasonal changes of day length.https://www.nature.com/articles/s41467-020-15384-9.epdf?author_access_token=2gousnzzVysFSY2LOSNbg9RgN0jAjWel9jnR3ZoTv0Nc8pcIcRYpgVd4ttbqvXb5MXS0MKODYOIhLGIQKIZv5Ow-j1ozo37n3k6BgZUEhCXYP-ph-YcOlHYiEHZXSlh8D2M46yMxpNzY7lyIT7dxBg%3D%3D
The internal clock allows cyanobacteria to anticipate daily changes of darkness and light, so the photosynthetic metabolism and growth can function properly.
This is an example showing scientific idea precedes evidence. Two thousand years ago, Chinese medicine have already advocated harmony between humanity and nature and asked people to keep living habit as going to work at sunrise and going to rest at sunset. Since the recent development in genetic and medical studies, people have began to seek scientific explanation for “timing” with circadian rhythm hypothesis. Researchers have also explored the convergence of environmental signals and internal circadian rhythms in photoperiodic flowering in plants, seasonal reproductive rhythms in mammals, and growth rhythms in Arabidopsis. The scientific evidence in cyanobacteria matched our expectation. However, sometimes, we see disagreement between evidence and expectation. In that case, we need to respect the evidence and re-organize expectation or hypothesis.
Anyhow, keeping a good sleep-wake habit is important to health!